Chemical Name: Tributylmethylammonium chloride
Synonyms: Methyltributylammonium chloride
CAS Number: 37093-28-2
Product Use: Phase-transfer catalyst, specialty chemical applications
Manufacturer and Supplier Information: Name, address, emergency phone number of manufacturer or supplier
Recommended Restrictions: Industrial and laboratory use only
Emergency Contact: Chemtrec 24-hour hotline, local poison control center
Classification: Acute toxicity (oral, dermal), Skin irritation, Eye irritation
Signal Word: Warning
Hazard Statements: Harmful if swallowed; causes skin and eye irritation
Pictograms: Exclamation mark (GHS07)
Precautionary Statements: Avoid breathing dust or vapors, wash hands thoroughly after handling, use only in a well-ventilated area, wear protective gloves and eyewear
Potential Health Effects: Eye contact may lead to redness and irritation; skin exposure often causes dermatitis-type reactions; ingestion produces nausea, headache, potential for more systemic impact
Environmental Hazards: Toxic to aquatic life with long-lasting effects
Chemical Identity: Tributylmethylammonium chloride
Chemical Formula: C13H30ClN
Molecular Weight: 235.84 g/mol
Purity: ≥ 98%
Impurities/Additives: Organic byproducts below 2%, proprietary stabilizers may be present in trace amounts
Component Breakdown: Tributylmethylammonium chloride 98–100%, water or unspecified residuals <2%
General: Move to fresh air, seek medical attention if symptoms persist
Inhalation: Take individual to area with fresh air; keep at rest, loosen tight clothing, call physician if breathing difficulty occurs
Skin Contact: Remove contaminated clothing, rinse affected area with soap and water for at least 15 minutes, seek medical assistance if irritation develops
Eye Contact: Flush eyes with water for 15–20 minutes; lift eyelids to ensure thorough rinsing; continue irrigation during transport to hospital if symptoms continue
Ingestion: Rinse mouth, do not induce vomiting, never give anything by mouth to an unconscious person, call a poison center or physician immediately
Note to Physician: Treat symptomatically, monitor for respiratory distress, supportive care as indicated
Suitable Extinguishing Media: Water spray, alcohol-resistant foam, dry chemical, carbon dioxide
Unsuitable Extinguishing Media: High-pressure water jets
Hazards from Combustion: Releases toxic fumes including hydrogen chloride, nitrogen oxides, carbon oxides
Protective Equipment for Firefighters: Firefighters must wear full protective clothing and self-contained breathing apparatus
Precautions for Firefighting: Cool unaffected containers with water spray, keep upwind of fire
Personal Precautions: Wear suitable protective clothing, gloves, safety eyewear, and respiratory protection as needed
Environmental Precautions: Prevent entry into drains, surface water, and groundwater; isolate spill
Methods for Cleaning Up: Use non-combustible absorbent material such as sand or vermiculite, sweep and place into containers for disposal according to local regulations, ventilate area
Decontamination: Wash site with water and detergent after material removal
Notification Requirements: Notify relevant local authorities if major spill occurs
Safe Handling: Handle in fume hood or well-ventilated space, minimize dust and vapor formation, avoid contact with skin, eyes, and clothing
Equipment Recommendations: Use corrosion-resistant containers and transfer lines, keep tightly sealed when not in use
Storage Conditions: Store in cool, dry, and well-ventilated location, keep container tightly closed, protect from direct sunlight and moisture
Incompatible Materials: Avoid contact with strong oxidizing agents and acids
Hygiene Measures: Wash hands before eating, after handling; take off contaminated clothing and wash before reuse
Control Parameters: No established occupational exposure limits for this compound, minimize exposure as precaution
Engineering Controls: Use local exhaust ventilation or general dilution ventilation
Personal Protection: Nitrile or neoprene gloves, chemical safety goggles, lab coat or apron, use respiratory protection if airborne concentration exceeds exposure limits or if ventilation is poor
Environmental Controls: Avoid releases to environment, use closed systems and secondary containment
Physical State: Solid or viscous liquid, appearance may vary with temperature
Color: White to off-white
Odor: Mild, amine-like
pH: Not determined (aqueous solutions may be mildly basic)
Melting Point: 45–51°C (dependent on purity)
Boiling Point: Decomposes before boiling
Flash Point: Not available (non-volatile solid)
Solubility: Soluble in water and polar organic solvents
Partition Coefficient (n-octanol/water): No data
Vapor Pressure: Not applicable (low volatility)
Density: Approx. 0.87 g/cm³
Viscosity: Not available
Autoignition Temperature: No data
Evaporation Rate: Not applicable
Chemical Stability: Stable under recommended use and storage conditions
Thermal Decomposition: Decomposes at elevated temperatures, releasing hydrogen chloride and nitrogen oxides
Reactivity: No hazardous polymerization, reacts with strong oxidizers and acids
Conditions to Avoid: Exposure to moisture, excessive heat, open flame
Incompatible Materials: Strong acids, strong oxidizers, moisture
Hazardous Decomposition Products: Carbon oxides, hydrogen chloride, nitrogen oxides
Acute Toxicity (Oral): LD50 expected to be 50–500 mg/kg (rat, estimated), toxic if swallowed
Acute Toxicity (Dermal): Harmful in contact with skin, may cause irritation
Acute Toxicity (Inhalation): Irritation to respiratory tract, no established inhalation toxicity values
Skin Corrosion/Irritation: Causes skin irritation, redness, possible burns with prolonged exposure
Serious Eye Damage/Irritation: Causes severe irritation, risk of eye injury
Respiratory or Skin Sensitization: No data confirming sensitizing effects
Repeated Dose Toxicity: Repeated exposure may cause dry or cracking skin, central nervous system effects possible
Mutagenicity/Carcinogenicity: No classification as mutagen or carcinogen, data absent
Reproductive Toxicity: Not evaluated in controlled animal studies
Other Information: Exposure symptoms include nausea, headache, dizziness, gastrointestinal distress; minimize contact to avoid long-term complications
Acute Aquatic Toxicity: Highly toxic to aquatic organisms, EC50 (algae/daphnia/fish) likely below 10 mg/L
Chronic Aquatic Toxicity: Long-term adverse effects in aquatic environment due to persistence
Persistence and Degradability: Limited biodegradability, slow breakdown in water and soil
Bioaccumulative Potential: Low to moderate potential for bioaccumulation
Mobility in Soil: Product migrates in soil and could enter groundwater
Other Adverse Effects: Do not release product into water bodies without treatment
Waste Treatment Methods: Dispose of waste and residues according to federal, state, and local regulations
Contaminated Packaging: Rinse out containers with suitable solvent before recycling or disposal
Incineration: Use licensed hazardous waste incineration facilities where permitted
Landfill Restrictions: Confirm with local authorities about landfill prohibition for hazardous chemicals
Precautions: Prevent product from entering sewers or watercourses
UN Number: 2810
UN Proper Shipping Name: Toxic liquid, organic, n.o.s. (contains tributylmethylammonium chloride)
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: III
Labels Required: Toxic label (skull and crossbones)
Marine Pollutant: Yes
Special Precautions for User: Secure containers to prevent movement during transport, comply with regulations regarding transport of hazardous materials
Road (ADR/RID), Air (IATA), Sea (IMDG): Regulated under all major transport codes
U.S. Regulations: Listed under TSCA inventory, reportable quantity for release to environment not specified, SARA Title III - not specifically listed for acute health hazards
Canadian Regulations: DSL/NDSL status, controlled product under WHMIS
European Regulations: REACH Pre-registered, CLP-classified according to hazard communication rules
Labeling Requirements: Hazard pictogram and signal word required, hazard and precautionary statements listed above
International Inventories: Present on major chemical inventories including AICS (Australia), IECSC (China), ENCS (Japan), KECI (Korea), PICCS (Philippines)
Workplace Limits: No established permissible exposure limit; recommend following local guidelines for exposure minimization
Other Information: Restrictions on release to aquatic environments align with national legislation
