Product Name: 1-Adamantyltrimethylammonium Hydroxide Solution
Synonyms: AdTMAH, Adamantyltrimethylammonium Hydroxide
CAS Number: 76534-67-7
Recommended Use: Zeolite synthesis, chemical research, manufacturing electronics, phase-transfer catalyst
Manufacturer/Supplier: Commercial chemical supplier information available on label
Emergency Contact: Refer to chemical supplier's emergency telephone number listed on packaging, Poison Control Center
GHS Classification: Skin Corrosion/Irritation (Category 1B), Serious Eye Damage (Category 1), Acute Toxicity - Oral (Category 4), Acute Toxicity - Inhalation (Category 4)
Signal Word: Danger
Hazard Statements: Causes severe skin burns and eye damage. Harmful if swallowed or inhaled. May cause respiratory irritation. Solutions spray, mist, or vapors cause burning sensation on skin or mucosa.
Pictograms: Corrosive, Exclamation mark
Precautionary Statements: Wear protective gloves and clothing. Avoid breathing vapor, mist or spray. Use only outdoors or in well-ventilated area. Wash thoroughly after handling. Do not eat, drink, or smoke while handling product. Seek immediate medical attention after exposure.
Chemical Name: 1-Adamantyltrimethylammonium Hydroxide
Common Name: AdTMAH
Concentration: 20–30% (by weight in aqueous solution); balance water
CAS Number: 76534-67-7
Impurities/Additives: Trace residuals from manufacturing process, not classified as hazardous in specified concentrations
Inhalation: Remove person to fresh air. Keep at rest in position comfortable for breathing. If symptoms persist or if breathing difficulty appears, seek immediate medical attention.
Skin Contact: Take off contaminated clothing. Rinse skin immediately with plenty of water for at least 15–20 minutes. Seek prompt medical advice.
Eye Contact: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing and get immediate medical attention.
Ingestion: DO NOT induce vomiting. Rinse mouth with water. Never give anything by mouth to an unconscious person. Get medical attention swiftly.
Notes to Physician: Treat as strong alkali exposure; may cause deep tissue damage and delayed symptoms. Gastric lavage and dilution therapy under medical supervision.
Suitable Extinguishing Media: Water spray, alcohol-resistant foam, dry chemical powder, or carbon dioxide for surrounding fire. Avoid direct water jet on product.
Specific Hazards: Not itself flammable but reacts with most metals to produce hydrogen gas, which forms explosive mixtures with air. Evolves toxic fumes under fire conditions (nitrogen oxides, carbon monoxide, carbon dioxide).
Protective Equipment for Firefighters: Wear positive pressure self-contained breathing apparatus (SCBA) and chemically protective clothing to prevent contact with skin and eyes.
Advice: Keep unnecessary personnel and unprotected persons away. Use water spray to cool surrounding containers. Avoid runoff entering drains or watercourses.
Personal Precautions: Use personal protective equipment such as respiratory protection, chemical goggles, face shield, and impervious gloves. Ensure adequate ventilation. Avoid skin and eye contact.
Environmental Precautions: Prevent further leakage or spillage if safe to do so. Do not allow product to reach drains, surface water, or soil. Notify local authorities if release contaminates environment.
Methods for Containment and Cleanup: Absorb with inert material such as sand, earth, or vermiculite. Place in chemical waste container for proper disposal. Clean contaminated area thoroughly with water. Ventilate area. Dispose of in accordance with local, regional, or national regulations.
Handling: Use in well-ventilated area or fume hood. Avoid breathing vapors, mist, or spray. Avoid contact with skin, eyes, and clothing. Wash hands after handling. Do not eat, drink, or smoke when using product. Keep containers tightly closed.
Storage Conditions: Store locked up in cool, dry, well-ventilated area away from incompatible substances (acids, oxidizers, metals). Keep container out of direct sunlight, and away from heat sources. Use only corrosion-resistant containers with resistant inner liner. Avoid storing near foods and feedstuffs.
Occupational Exposure Limits: No established limits specific to AdTMAH, but handle as strong base chemical
Engineering Controls: Use chemical fume hood, eyewash station, and safety shower at workstation. Ensure good general ventilation to keep airborne concentrations low.
Personal Protective Equipment:
- Respiratory Protection: Use NIOSH/MSHA approved respirator for protection against chemical vapors or mists.
- Hand Protection: Wear suitable chemical-resistant gloves (nitrile, neoprene, butyl rubber).
- Eye Protection: Chemical safety goggles and face shield.
- Skin & Body Protection: Long-sleeved lab coat, apron, closed-toe chemical-resistant footwear. Remove contaminated clothing promptly.
Appearance: Clear to pale yellow liquid
Odor: Ammoniacal or slight organic odor
pH: Highly alkaline (typically >13)
Melting Point/Freezing Point: Approximately 0°C (as aqueous solution)
Boiling Point: ~100°C (water-based solution)
Solubility: Completely miscible with water
Vapor Pressure: Low (similar to water)
Relative Density: 1.02–1.10 (varies with concentration)
Viscosity: Moderate, similar to water
Flash Point: Not applicable (aqueous solution)
Evaporation Rate: Comparable to water
Decomposition Temperature: Decomposes on heating above 100°C, emitting toxic fumes
Other Properties: Corrosive to tissue, metals
Chemical Stability: Stable at room temperature in closed containers under recommended storage conditions. Sustained high temperatures and exposure to air accelerate decomposition.
Possibility of Hazardous Reactions: Reacts vigorously with acids producing heat and toxic vapors. Contact with metals liberates hydrogen gas. Incompatible with oxidizing agents and strong acids.
Conditions to Avoid: Heat, open flames, exposure to incompatible substances, and prolonged storage.
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide, ammonia, methylamines.
Polymerization: Will not occur under normal handling and storage.
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Acute Effects: Corrosive to skin and eyes, causing severe burns. Harmful if inhaled or ingested. Causes severe irritation to mucous membranes. Respiratory distress and coughing can develop quickly.
Chronic Effects: Prolonged or repeated exposure may result in dermatitis or ulceration. Inhalation of mists may damage respiratory tract. May cause delayed pulmonary edema.
LD50 (Oral, Rat): Data not fully available; similar compounds show moderate toxicity at 100–400 mg/kg.
Mutagenicity/Carcinogenicity/Reproductive Toxicity: Not classified as carcinogenic or teratogenic by IARC, NTP, or OSHA.
Other Hazards: Strong alkalinity can cause permanent loss of vision from eye contact. Potent membrane irritant.
Ecotoxicity: Harmful to aquatic organisms due to high pH. Can alter pH of water bodies and cause ecological imbalance.
Persistence & Degradability: Solution dissociates fully in water. Organic cation undergoes slow biodegradation.
Bioaccumulative Potential: Low expected bioaccumulation due to water solubility and instability of cation in environment.
Mobility in Soil: Highly mobile in water; not significantly absorbed by soil particles.
Other Effects: Avoid spillage or release into drains, rivers, or aquatic environments to prevent pH shifts and toxic effects on aquatic plants and animals.
Waste Disposal Methods: Treat as hazardous waste. Neutralize solution with diluted acid under controlled conditions before disposal according to local and national regulations. Collect in suitable containers and label clearly. Do not discharge product to sewer without proper treatment.
Packaging Disposal: Rinse thoroughly before discarding as non-hazardous waste, or dispose as hazardous chemical packaging if not decontaminated. Follow all applicable disposal guidelines for alkali residues and used personal protection equipment.
UN Number: UN3267
Proper Shipping Name: Corrosive Liquid, Basic, Organic, N.O.S. (contains 1-Adamantyltrimethylammonium Hydroxide Solution)
Transport Hazard Class: 8 (Corrosive materials)
Packing Group: II
Environmental Hazards: Avoid release to the environment. Marine pollutant not classified.
Special Precautions: Secure upright containers. Avoid transport with strong acids or oxidizers. Emergency response guide for spills during transit required.
TSCA Status: Listed or in compliance
OSHA Hazard Communication: Classified as hazardous, OSHA 29 CFR 1910.1200
SARA 313: Not listed
REACH Registration: Registration or exemption criteria fulfilled in applicable regions
Canadian WHMIS Classification: D2B (Toxic), E (Corrosive)
California Prop 65: Not listed
Other Regulations: Ensure compliance with all relevant national, regional, and local regulations regarding chemical handling, transport, and disposal. Consult local environmental agency for permits or advisories.
